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Gallbladder Cancer Treatment

Gallbladder Cancer Treatment in India

What Is Gallbladder Cancer?

Gallbladder cancer is a rare type of cancer that originates when malignant or cancer cells reside in the tissues of the gallbladder, located just below the liver. The gallbladder is a tiny pear-shaped organ that stores bile produced by the liver. The bile duct is a tube that connects the liver to the gallbladder and discharges bile into the common bile duct.

Gallbladder cancer is often diagnosed late, as symptoms typically appear only after the disease has progressed. Early diagnosis greatly improves treatment outcomes.


Symptoms of Gallbladder Cancer

  • Severe abdominal discomfort in the upper right area of the belly
  • Frequent vomiting
  • Mass in the abdomen
  • Jaundice
  • Itchy skin
  • Dark urine
  • Oily or white feces
  • Sudden weight loss
  • Loss of appetite
  • Abdominal bloating
  • Fever
  • Yellowing of the skin and eyes

How Does Gallbladder Cancer Spread?

Cancer can metastasize (spread) through:

  • Tissue: Invading nearby tissues
  • Lymph System: Spreading through the lymphatic system
  • Blood: Traveling through blood vessels to other body parts

Causes and Risk Factors

The exact cause is unknown, but several factors increase the risk:

  • Smoking
  • Chemical exposure (e.g., in textile/rubber industries)
  • Primary sclerosing cholangitis (PSC)
  • Bile duct cysts
  • Age (typically diagnosed at age 72)
  • Obesity
  • Gallbladder polyps and infections
  • Salmonella infection
  • Poor diet
  • Gallstones (increase risk but don't guarantee cancer)

Diagnosis of Gallbladder Cancer

Diagnosis and staging often occur simultaneously. Tests may include:

  1. Physical exam and medical history
  2. Liver function tests
  3. Blood tests
  4. CT scan
  5. Ultrasound
  6. PTC (Percutaneous Transhepatic Cholangiography)
  7. Endoscopic ultrasound
  8. MRI
  9. Laparoscopy
  10. Biopsy

Factors affecting prognosis and treatment:

  • Stage and spread of cancer
  • Surgical removability
  • Cancer cell type
  • Whether it is a recurrence

Treatment Options

You may consult multiple specialists:

  • Surgical oncologist for cancer surgery
  • Medical oncologist for chemotherapy
  • Radiation oncologist for radiotherapy
  • Gastroenterologist for digestive health

Localized Gallbladder Cancer

  • Radiation therapy: High-energy X-rays destroy cancer cells
  • Chemotherapy: Drugs kill or stop cancer cell growth
  • Surgery:
    • Cholecystectomy – Removal of the gallbladder
    • Radical gallbladder resection – Removal of the gallbladder with surrounding tissue

Advanced or Metastatic Cancer

  • Palliative Surgery:
    • Biliary bypass surgery
    • Endoscopic stent placement
  • Chemo or chemo-radiotherapy: To shrink tumors and possibly allow later surgery

Note: If the tumor is confined to the inner lining and the gallbladder is already removed, monitoring may be sufficient. Otherwise, more extensive surgery is needed.


Laparoscopic Surgery

Modern gallbladder cancer surgery is often performed laparoscopically with minimal incisions. An extended cholecystectomy involves removing the gallbladder and additional surrounding tissues.


Choosing a Hospital for Gallbladder Cancer Treatment in India

India is a popular destination for cancer care due to:

  • Affordable pricing
  • Advanced diagnostic and therapeutic equipment
  • Accredited hospitals (NABH, JCI)
  • Expert oncologists and surgeons
  • International patient assistance

Factors to consider:

  • Quality certificates
  • Hospital and transport location
  • Team experience
  • Technology available
  • Global patient services

Frequently Asked Questions

Q: Can a Cancerous Gallbladder Be Removed?

A: Yes. An extended (or radical) cholecystectomy is typically performed to prevent recurrence.

Q: What Percentage of Gallbladder Cancers Are Resectable?

A: Only about 10% are resectable at surgery time; nearly 50% have lymph node metastases.

Q: What Causes Gallbladder Tumors?

A: Gallstones are a leading cause. They cause chronic inflammation, which can lead to cancer.

Q: How Long Is Bed Rest After Gallbladder Surgery?

A: Expect sleep disruptions for 1–2 weeks. Adequate rest is vital for recovery.

Q: What Is the Fastest Way to Recover from Gallbladder Surgery?

A: Rest completely for 24 hours post-surgery. Then, walk regularly and listen to your body to avoid overexertion.

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